Humanity is on course to transgress multiple global “tipping points” that could lead to irreversible instability or the complete collapse of ecological and institutional systems, a United Nations report warned Wednesday.

The third annual Interconnected Disaster Risks report from the U.N. University’s Institute for Environment and Human Security in Bonn, Germany, found that drastic changes will occur if urgent actions are not taken around six moments when sociological systems are no longer able to buffer risks.