Radically transformed from its ancient origin as a vast tidal-influenced freshwater marsh, the Sacramento-San Joaquin Delta ecosystem is in constant flux, influenced by factors within the estuary itself and the massive watersheds that drain though it into the Pacific Ocean. Lately, however, scientists say the rate of change has kicked into overdrive, fueled in part by climate change, and is limiting the ability of science and Delta water managers to keep up. The rapid pace of upheaval demands a new way of conducting science and managing water in the troubled estuary that is central to California’s water conveyance system.